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Pagibaximab binds to all
staphylococci tested and promotes
ingestion and killing of the
bacteria by white blood cells. Pre-
clinical studies have shown that
the antibody provides protection in
relevant animal models replicating
the worst-case infection scenario
in the premature baby. In
addition, studies have shown that
it also binds to enterococci and
group A streptococci, that express
a common LTA in their membrane.
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